Article
NKX2-6 mutation predisposes to familial atrial fibrillation.
International journal of molecular medicine - 1 Dec 2014
Wang Jun, Zhang Dai-Fu, Sun Yu-Min, Li Ruo-Gu, Qiu Xing-Biao, Qu Xin-Kai, Liu Xu, Fang Wei-Yi, Yang Yi-Qing
Abstract excerpt
Atrial fibrillation (AF) is the most common form of sustained cardiac arrhythmia and is associated with substantially increased morbidity and mortality rates. Aggregating evidence demonstrates that genetic defects are involved in the pathogenesis of AF and a number of AF-associated genes have been identified. Nevertheless, AF is a genetically heterogeneous disorder and the genetic components underpinning AF in an...
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