Article
Antiproliferative effects of phenylaminonaphthoquinones are increased by ascorbate and associated with the appearance of a senescent phenotype in human bladder cancer cells.
Biochemical and biophysical research communications - 19 Apr 2013
Felipe K B, Benites J, Glorieux C, Sid B, Valenzuela M, Kviecinski M R, Pedrosa R C, Valderrama J A, Levêque Ph, Gallez B, Verrax J, Buc Calderon P
Abstract excerpt
Quinone-containing molecules have been developed against cancer mainly for their redox cycling ability leading to reactive oxygen species (ROS) formation. We have previously shown that donor-acceptor phenylaminonaphthoquinones are biologically active against a panel of cancer cells. In this repor...
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