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Article

Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response.

The Journal of pathology - 1 Jul 2013

Sielska Malgorzata, Przanowski Piotr, Wylot Bartosz, Gabrusiewicz Konrad, Maleszewska Marta, Kijewska Magdalena, Zawadzka Malgorzata, Kucharska Joanna, Vinnakota Katyayni, Kettenmann Helmut, Kotulska Katarzyna, Grajkowska Wieslawa, Kaminska Bozena

Abstract excerpt

Gliomas attract brain-resident (microglia) and peripheral macrophages and reprogram these cells into immunosuppressive, pro-invasive cells. M-CSF (macrophage colony-stimulating factor, encoded by the CSF1 gene) has been implicated in the control of recruitment and polarization of macrophages in several cancers. We found that murine GL261 glioma cells overexpress GM-CSF (granulocyte-macrophage colony-stimulating...

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Source

Identifiers

PMID: 23520016
DOI: 10.1002/path.4192

Genes

CSF2
CSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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