Article
Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas.
The Journal of pathology - 1 Sept 2008
Komohara Y, Ohnishi K, Kuratsu J, Takeya M
Abstract excerpt
Within tumours, many non-neoplastic cells such as fibroblasts, endothelial cells, and macrophages assist tumour growth by producing various growth factors and pro-angiogenic cytokines. Various tumour-derived molecules drive tumour-associated macrophages towards an anti-inflammatory phenotype (M2) and thus promoting tumour growth. Here we investigated microglia/macrophage differentiation in glioma tissues by means...
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