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Article

Use of RT-defective HIV virions: new tool to evaluate specific response in chronic asymptomatic HIV-infected individuals.

PloS one - 1 Jan 2013

Guardo Alberto Crespo, Alvarez-Fernández Carmen, Arberas Hodei, García-Pérez Javier, García Felipe, Bargalló Manuel Enric, Maleno María José, Gatell José María, Mothe Beatriz, Alcami José, Sánchez-Palomino Sonsoles, Plana Montserrat

Abstract excerpt

BACKGROUND: Generation of new reagents that can be used to screen or monitor HIV-1-specific responses constituted an interesting field in the development of HIV vaccines to improve their efficacy. METHODS: We have evaluated the specific T cell response against different types of NL4-3 virions (including NL4-3 aldrithiol-2 treated, NL4-3/ΔRT and R5 envelopes: NL4-3/ΔRT/ΔEnv[AC10] and NL4-3/ΔRT/ΔEnv[Bal]) and...

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Share to Asymptomatic Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23516578
DOI: 10.1371/journal.pone.0058927
PMCID: PMC3597525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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