Article
Regulation of presynaptic anchoring of the scaffold protein Bassoon by phosphorylation-dependent interaction with 14-3-3 adaptor proteins.
PloS one - 1 Jan 2013
Schröder Markus S, Stellmacher Anne, Romorini Stefano, Marini Claudia, Montenegro-Venegas Carolina, Altrock Wilko D, Gundelfinger Eckart D, Fejtova Anna
Abstract excerpt
The proper organization of the presynaptic cytomatrix at the active zone is essential for reliable neurotransmitter release from neurons. Despite of the virtual stability of this tightly interconnected proteinaceous network it becomes increasingly clear that regulated dynamic changes of its composition play an important role in the processes of synaptic plasticity. Bassoon, a core component of the presynaptic...
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