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Article

NPM1, FLT3, and c-KIT mutations in pediatric acute myeloid leukemia in Russian population.

Journal of pediatric hematology/oncology - 1 Apr 2013

Yatsenko Yuliya, Kalennik Olga, Maschan Mikhail, Kalinina Irina, Maschan Alexey, Nasedkina Tatyana

Abstract excerpt

We evaluated frequencies of NPM1, FLT3, c-KIT mutations in childhood acute myeloid leukemia (AML) in Russia and assessed prognostic relevance of the mutations. RNA and DNA were extracted from bone marrow samples of 186 (106 male and 80 female) pediatric patients younger than 17 year with de novo AML. Mutations and chromosomal rearrangements were detected by sequencing of a corresponding gene. NPM1 mutations were...

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Source

Identifiers

PMID: 23511494
DOI: 10.1097/MPH.0b013e318286d261

Genes

FLT3
NPM1
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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