Article
Genetics of venous thrombosis: insights from a new genome wide association study.
PloS one - 1 Jan 2011
Germain Marine, Saut Noémie, Greliche Nicolas, Dina Christian, Lambert Jean-Charles, Perret Claire, Cohen William, Oudot-Mellakh Tiphaine, Antoni Guillemette, Alessi Marie-Christine, Zelenika Diana, Cambien François, Tiret Laurence, Bertrand Marion, Dupuy Anne-Marie, Letenneur Luc, Lathrop Mark, Emmerich Joseph, Amouyel Philippe, Trégouët David-Alexandre, Morange Pierre-Emmanuel
Abstract excerpt
BACKGROUND: Venous Thrombosis (VT) is a common multifactorial disease associated with a major public health burden. Genetics factors are known to contribute to the susceptibility of the disease but how many genes are involved and their contribution to VT risk still remain obscure. We aimed to identify genetic variants associated with VT risk. METHODOLOGY/PRINCIPAL FINDINGS: We conducted a genome-wide association...
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