A follow-up study of a genome-wide association scan identifies a susceptibility locus for venous thrombosis on chromosome 6p24.1.

doi:10.1016/j.ajhg.2010.02.011

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A follow-up study of a genome-wide association scan identifies a susceptibility locus for venous thrombosis on chromosome 6p24.1.

American journal of human genetics - 9 Apr 2010

Morange Pierre-Emmanuel, Bezemer Irene, Saut Noémie, Bare Lance, Burgos Gwenaelle, Brocheton Jessy, Durand Hervé, Biron-Andreani Christine, Schved Jean-Francois, Pernod Gilles, Galan Pilar, Drouet Ludovic, Zelenika Diana, Germain Marine, Nicaud Viviane, Heath Simon, Ninio Ewa, Delluc Aurélien, Münzel Thomas, Zeller Tanja, Brand-Herrmann Stefan-Martin, Alessi Marie-Christine, Tiret Laurence, Lathrop Mark, Cambien François, Blankenberg Stefan, Emmerich Joseph, Trégouët David-Alexandre, Rosendaal Frits R

Abstract excerpt

To identify genetic susceptibility factors conferring increased risk of venous thrombosis (VT), we conducted a multistage study, following results of a previously published GWAS that failed to detect loci for developing VT. Using a collection of 5862 cases with VT and 7112 healthy controls, we identified the HIVEP1 locus on chromosome 6p24.1 as a susceptibility locus for VT. Indeed, the HIVEP1 rs169713C allele...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 6

Share to DNA-Binding Proteins

Share to Follow-Up Studies

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Transcription Factors

Share to Venous Thrombosis

Source

Open in PubMed Open full text

Identifiers

PMID: 20226436
DOI: 10.1016/j.ajhg.2010.02.011
PMCID: PMC2850428

Genes

HIVEP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A follow-up study of a genome-wide association scan identifies a susceptibility locus for venous thrombosis on chromosome 6p24.1.PMID 20226436Read ↗

Genetics of venous thrombosis: insights from a new genome wide association study.Semantic proximity Read ↗

Genetics of Venous Thrombosis: update in 2015.Semantic proximity Read ↗

Current knowledge on the genetics of incident venous thrombosis.Semantic proximity Read ↗

Venous thromboembolic disease genetics: from variants to function.Semantic proximity Read ↗

What is currently known about the genetics of venous thromboembolism at the dawn of next generation sequencing technologies.Semantic proximity Read ↗

GENETIC DETERMINANTS OF THROMBOSIS.Semantic proximity Read ↗

Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism.Semantic proximity Read ↗

Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.Semantic proximity Read ↗

Genetic variations and their influence on risk and treatment of venous thrombosis.Semantic proximity Read ↗

Cross-Ancestry Investigation of Venous Thromboembolism Genomic PredictorsSemantic proximity Read ↗

A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis.Semantic proximity Read ↗

Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.