Article
Interactions of established risk factors and a GWAS-based genetic risk score on the risk of venous thromboembolism.
Thrombosis and haemostasis - 27 Sept 2016
Crous-Bou Marta, De Vivo Immaculata, Camargo Carlos A, Varraso Raphaëlle, Grodstein Francine, Jensen Majken K, Kraft Peter, Goldhaber Samuel Z, Lindström Sara, Kabrhel Christopher
Abstract excerpt
Multiple genetic and environmental risk factors contribute to venous thromboembolism (VTE) risk. Understanding how genes and environmental risk factors interact may provide key insight into the pathophysiology of VTE and may identify opportunities for targeted prevention and treatment. It was our aim to examine the main effects and the potential effect-modification between single nucleotide polymorphisms (SNPs)...
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