Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combinatorial control of Th17 and Th1 cell functions by genetic variations in genes associated with the interleukin-23 signaling pathway in spondyloarthritis.

Arthritis and rheumatism - 1 Jun 2013

Coffre Maryaline, Roumier Mathilde, Rybczynska Magda, Sechet Emmanuel, Law Helen K W, Gossec Laure, Dougados Maxime, Bianchi Elisabetta, Rogge Lars

Abstract excerpt

OBJECTIVE: Recent genome-wide association studies have revealed numerous genetic associations between specific single-nucleotide polymorphisms (SNPs) and immune-mediated inflammatory diseases. The current challenge is to identify associations of the genetic variants with effector mechanisms impli...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4-Positive T-Lymphocytes
Share to Cytokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation

Share to Interleukin-23

Share to Real-Time Polymerase Chain Reaction

Share to Spondylarthropathies

Share to Th1 Cells

Share to Th17 Cells

Source

Identifiers

PMID: 23508476
DOI: 10.1002/art.37936

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23508476-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combinatorial control of Th17 and Th1 cell functions by genetic variations in genes associated with the interleukin-23 signaling pathway in spondyloarthritis.PMID 23508476Read ↗

The IL-17/IL-23 Axis and Its Genetic Contribution to Psoriatic Arthritis.Semantic proximity Read ↗

The genetic backbone of ankylosing spondylitis: how knowledge of genetic susceptibility informs our understanding and management of disease.Semantic proximity Read ↗

Illuminating the impact of γδ T cells in man and mice in spondylarthritides.Semantic proximity Read ↗

From the Genetics of Ankylosing Spondylitis to New Biology and Drug Target Discovery.Semantic proximity Read ↗

The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans.Semantic proximity Read ↗

Ankylosing Spondylitis: From Cells to GenesSemantic proximity Read ↗

The Genetics of SpondyloarthritisSemantic proximity Read ↗

Perspectives on the Genetic Associations of Ankylosing SpondylitisSemantic proximity Read ↗

Genetics and Functional Genomics of SpondyloarthritisSemantic proximity Read ↗

Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions.Semantic proximity Read ↗

How to translate genetic findings into clinical applications in spondyloarthritis?Semantic proximity Read ↗

Association of interleukin 23 receptor variants with psoriatic arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.