Article
Inhibitory effects of in vivo oxidized high-density lipoproteins on platelet aggregation: evidence from patients with abetalipoproteinemia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2013
Calzada Catherine, Véricel Evelyne, Colas Romain, Guillot Nicolas, El Khoury Graziella, Drai Jocelyne, Sassolas Agnès, Peretti Noël, Ponsin Gabriel, Lagarde Michel, Moulin Philippe
Abstract excerpt
There is evidence that high-density lipoproteins (HDLs) may regulate platelet function, but disparate results exist regarding the effects of oxidized HDLs on platelets. The objective of our study was to determine the role of in vivo oxidized HDLs on platelet aggregation. Platelet aggregation and redox status were investigated in 5 patients with abetalipoproteinemia (ABLP) or homozygous hypobetalipoproteinemia,...
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