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Article

Oxidative stress and platelet activation in homozygous homocystinuria.

Circulation - 4 Sept 2001

Davì G, Di Minno G, Coppola A, Andria G, Cerbone A M, Madonna P, Tufano A, Falco A, Marchesani P, Ciabattoni G, Patrono C

Abstract excerpt

BACKGROUND: Severe hyperhomocysteinemia due to cystathionine beta-synthase deficiency (CbetaSD) is associated with early atherothrombotic vascular disease. Homocysteine may exert its effects by promoting oxidative damage. In the present study, we investigated whether in vivo formation of 8-iso-pr...

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PMID: 11535567
DOI: 10.1161/hc3501.095287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11535567-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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