Pharmacologic elevation of high-density lipoproteins: recent insights on mechanism of action and atherosclerosis protection

Abstract excerpt

PURPOSE OF REVIEW: Despite the best efforts in reduction of low-density lipoprotein cholesterol, most cardiovascular events are not being prevented. Because high-density lipoprotein (HDL) promotes reverse cholesterol transport and other antiatherogenic effects, interventions aimed at raising HDL cholesterol or mimicking its beneficial effects may greatly improve treatment and prevention of cardiovascular disease....

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