Article
Behavior of an Aeromonas hydrophila aroA live vaccine in water microcosms.
Applied and environmental microbiology - 1 May 2004
Vivas José, Carracedo Begoña, Riaño Jorge, Razquin Blanca E, López-Fierro Pilar, Acosta Félix, Naharro Germán, Villena Alberto J
Abstract excerpt
Genetically modified auxotrophic mutants of different fish pathogens have been used as live vaccines in laboratory experiments, but the behavior of the strains after release into aquatic ecosystems has not been characterized. We previously constructed and characterized an aroA mutant of Aeromonas hydrophila and studied the protection afforded by this mutant as a live vaccine in rainbow trout. In this work, we...
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