Article
The number of cysteine residues per mole in apolipoprotein E affects systematically synchronous neural interactions in women's healthy brains.
Experimental brain research - 1 May 2013
Leuthold Arthur C, Mahan Margaret Y, Stanwyck John J, Georgopoulos Angeliki, Georgopoulos Apostolos P
Abstract excerpt
Apolipoprotein E (apoE) is involved in lipid metabolism in the brain, but its effects on brain function are not understood. Three apoE isoforms (E4, E3, and E2) are the result of cysteine-arginine interchanges at two sites: there are zero interchanges in E4, one interchange in E3, and two interchanges in E2. The resulting six apoE genotypes (E4/4, E4/3, E4/2, E3/3, E3/2, E2/2) yield five groups with respect to...
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