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Article

The deletion variant of α2b-adrenergic receptor is associated with decreased risk in Alzheimer's disease and mild cognitive impairment.

Journal of the neurological sciences - 15 May 2013

Koutroumani Maria, Daniilidou Makrina, Giannakouros Thomas, Proitsi Petroula, Liapi Despina, Germanou Antonia, Nikolakaki Eleni, Tsolaki Magda

Abstract excerpt

A common genetic polymorphism of the α2b-adrenergic receptor (ADRA2B) resulting in a deletion of three glutamic acids located on the third intracellular loop of the protein, has been associated with memory formation enhanced by emotional events. Additionally, there are several studies documenting the involvement of this polymorphism in other types of cognition, such as episodic memory. The aim of this study was...

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PMID: 23499426
DOI: 10.1016/j.jns.2013.02.003

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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