Article
Melanocortin-3-receptor promoter polymorphism associated with tuberculosis susceptibility does not influence protein expression.
BMC research notes - 15 Mar 2013
Eggert Marlene, Pfob Martina, Steinlein Ortrud K
Abstract excerpt
BACKGROUND: The melanocortin-3-receptor (MC3R) is a member of the G-protein coupled receptor family that mediate cellular response through the cyclic adenosine monophosphate signalling pathway. In the promoter region of MC3R the polymorphism rs6127698 has previously been shown to be strongly associated with tuberculosis susceptibility. It is predicted to generate an alternative transcription factor binding site....
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