Article
Analysis of -631 and -475 interleukin-2 promoter single nucleotide polymorphisms in multiple sclerosis.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Oct 2002
Fedetz M, Alcina A, Fernández O, Guerrero M, Delgado C, Matesanz F
Abstract excerpt
We have analysed the interleukin-2 (IL-2) promoter single nucleotide polymorphisms -475 A/T and -631 G/A, relative to the initiation codon, in patients with multiple sclerosis (MS) and in healthy controls. Both groups showed a very low frequency of T at -475 and A at -631. Our results suggest that these polymorphisms do not contribute to MS susceptibility.
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