Article
Schizophrenia susceptibility and NMDA-receptor mediated signalling: an association study involving 32 tagSNPs of DAO, DAOA, PPP3CC, and DTNBP1 genes.
BMC medical genetics - 9 Mar 2013
Sacchetti Emilio, Scassellati Catia, Minelli Alessandra, Valsecchi Paolo, Bonvicini Cristian, Pasqualetti Patrizio, Galluzzo Alessandro, Pioli Rosaria, Gennarelli Massimo
Abstract excerpt
BACKGROUND: Recent studies supported associations between four NMDA-receptor-mediated signalling genes (D-amino acid oxidase, DAO; D-amino acid oxidase activator, DAOA; protein phosphatase 3 catalytic subunit gamma isoform, PPP3CC; dystrobrevin-binding protein 1, DTNBP1) and schizophrenia susceptibility, even though with contrasting results. METHODS: In an attempt to replicate these findings for the first time in...
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