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Article

Yes-associated protein (yap) is required for early embryonic development in zebrafish (danio rerio).

International journal of biological sciences - 1 Jan 2013

Hu Jingying, Sun Shuna, Jiang Qiu, Sun Shaoyang, Wang Wei, Gui Yonghao, Song Houyan

Abstract excerpt

The hippo (Hpo) signaling pathway plays a critical role in regulation of organ size. The kinase cascade ultimately antagonizes the transcriptional co-activator Yki/YAP, which is a key regulator of cell proliferation and apoptosis. In this study, we performed a knocking down study using antisense morpholino (MO) reagents and found that zebrafish YAP, a key transcriptional co-activator of Hpo pathway, plays a...

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Identifiers

PMID: 23494967
DOI: 10.7150/ijbs.4887
PMCID: PMC3596712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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