Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CFH haplotypes and ARMS2, C2, C3, and CFB alleles show association with susceptibility to age-related macular degeneration in Mexicans.

Molecular vision - 1 Jan 2014

Contreras Alejandra V, Zenteno Juan Carlos, Fernández-López Juan Carlos, Rodríguez-Corona Ulises, Falfán-Valencia Ramcés, Sebastian Leticia, Morales Fabiola, Ochoa-Contreras Daniel, Carnevale Alessandra, Silva-Zolezzi Irma

Abstract excerpt

PURPOSE: To evaluate the contribution of genetic variants of complement factor H (CFH), complement component 2 and 3 (C2 and C3), complement factor B (CFB), and age-related maculopathy susceptibility 2 (ARMS2) to age-related macular degeneration (AMD) risk in the Mexican Mestizo population. METHODS: Analysis included 282 unrelated Mexican patients with advanced AMD, 205 healthy controls, and 280 population...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement C2
Share to Complement C3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement Factor B

Share to Complement Factor H

Share to Macular Degeneration

Share to Mexico

Share to Open Reading Frames

Share to Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24453474
PMCID: PMC3891434

Genes

CFH
ARMS2
CFB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CFH haplotypes and ARMS2, C2, C3, and CFB alleles show association with susceptibility to age-related macular degeneration in Mexicans.PMID 24453474Read ↗

Susceptibility to advanced age-related macular degeneration and alleles of complement factor H, complement factor B, complement component 2, complement component 3, and age-related maculopathy susceptibility 2 genes in a Mexican population.Semantic proximity Read ↗

Association analysis of CFH and ARMS2 gene polymorphisms in a Brazilian cohort with age-related macular degeneration.Semantic proximity Read ↗

CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD.Semantic proximity Read ↗

The molecular genetic basis of age-related macular degeneration: an overview.Semantic proximity Read ↗

Risk alleles in CFH and ARMS2 and the long-term natural history of age-related macular degeneration: the Beaver Dam Eye Study.Semantic proximity Read ↗

Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications.Semantic proximity Read ↗

Association Between Complement Factor C2/C3/CFB/CFH Polymorphisms and Age-Related Macular Degeneration: A Meta-Analysis.Semantic proximity Read ↗

Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss.Semantic proximity Read ↗

Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration.Semantic proximity Read ↗

Association of genetic variants rs641153 (CFB), rs2230199 (C3), and rs1410996 (CFH) with age-related macular degeneration in a Brazilian population.Semantic proximity Read ↗

Susceptibility genes and progression in age-related maculopathy: a study of single eyes.Semantic proximity Read ↗

Complement Factor H Polymorphism, Complement Activators, and Risk of Age-Related Macular DegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.