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Polymorphisms in oxidative stress-related genes and mortality in breast cancer patients--potential differential effects by radiotherapy?

Breast (Edinburgh, Scotland) - 1 Oct 2013

Seibold Petra, Hall Per, Schoof Nils, Nevanlinna Heli, Heikkinen Tuomas, Benner Axel, Liu Jianjun, Schmezer Peter, Popanda Odilia, Flesch-Janys Dieter, Chang-Claude Jenny

Abstract excerpt

We assessed whether variants in 22 oxidative stress-related genes are associated with mortality of breast cancer patients and whether the associations differ according to radiotherapy. Using a prospective cohort of 1348 postmenopausal breast cancer patients, we estimated hazard ratios (HR) and 95% confidence intervals (CI) for 109 single nucleotide polymorphisms (SNPs) using Cox proportional hazards regression....

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Identifiers

PMID: 23489758
DOI: 10.1016/j.breast.2013.02.008

Genes

NQO1
PRDX6
PRDX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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