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Article

Degradome sequencing reveals an endogenous microRNA target in C. elegans.

FEBS letters - 2 Apr 2013

Park June Hyun, Ahn Soungyub, Kim Soyoung, Lee Junho, Nam Jin-Wu, Shin Chanseok

Abstract excerpt

Caenorhabditis elegans microRNAs (miRNAs) bind to partially complementary sequences in the 3' untranslated region of target mRNAs, resulting in translational repression through mRNA destabilization. High-throughput sequencing of RNA cleavage fragments was performed to directly detect miRNA-directed cleavage targets in adult stage C. elegans. From this analysis, we found that miR-249 directed the cleavage of the...

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PMID: 23485825
DOI: 10.1016/j.febslet.2013.02.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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