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Article

Mismatch repair and response to DNA-damaging antitumour therapies.

European journal of cancer (Oxford, England : 1990) - 1 Oct 2003

Bignami M, Casorelli I, Karran P

Abstract excerpt

Most antitumour therapies damage tumour cell DNA either directly or indirectly. DNA damage responses, and particularly DNA repair, influence the outcome of therapy. Because DNA repair normally excises lethal DNA lesions, it is intuitive that efficient repair will contribute to intrinsic drug resistance. Indeed, in certain circumstances reduced levels of DNA nucleotide excision repair are associated with a good...

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Identifiers

PMID: 14522371
DOI: 10.1016/s0959-8049(03)00569-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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