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Article

Transcriptional specificity in various p53-mutant cells.

Anticancer research - 1 Mar 2013

Okaichi Kumio, Izumi Nanaka, Takamura Yuma, Fukui Shoichi, Kudo Takashi

Abstract excerpt

Mutation of the tumor suppressor gene p53 is the most common genetic alteration observed in human tumors. However, the relationship between the mutation point of p53 and the transcriptional specificity is not so obvious. We prepared Saos-2 cells with various mutations of p53 that are found in human tumors, and examined the resulting transcriptional alterations in the cells. Loss of function and gain of function...

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Source

Identifiers

PMID: 23482763

Genes

PIWIL4
CADPS2
TRIM9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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