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Article

Interaction of neuropeptide Y genotype and childhood emotional maltreatment on brain activity during emotional processing.

Social cognitive and affective neuroscience - 1 May 2014

Opmeer Esther M, Kortekaas Rudie, van Tol Marie-José, van der Wee Nic J A, Woudstra Saskia, van Buchem Mark A, Penninx Brenda W J H, Veltman Dick J, Aleman André

Abstract excerpt

Neuropeptide Y (NPY) has been associated with stress reactivity in affective disorders and is most densely expressed in the amygdala. An important stressor associated with affective disorders is the experience of childhood emotional maltreatment (CEM). We investigated whether the interaction of NPY risk genotype and CEM would affect brain activation. From The Netherlands Study of Depression and Anxiety, 33...

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Source

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Identifiers

PMID: 23482625
DOI: 10.1093/scan/nst025
PMCID: PMC4014098

Genes

NPY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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