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Article

A trans-spliced telomerase RNA dictates telomere synthesis in Trypanosoma brucei.

Cell research - 1 Apr 2013

Sandhu Ranjodh, Sanford Samantha, Basu Shrabani, Park Mina, Pandya Unnati M, Li Bibo, Chakrabarti Kausik

Abstract excerpt

Telomerase is a ribonucleoprotein enzyme typically required for sustained cell proliferation. Although both telomerase activity and the telomerase catalytic protein component, TbTERT, have been identified in the eukaryotic pathogen Trypanosoma brucei, the RNA molecule that dictates telomere synthesis remains unknown. Here, we identify the RNA component of Trypanosoma brucei telomerase, TbTR, and provide...

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Identifiers

PMID: 23478302
DOI: 10.1038/cr.2013.35
PMCID: PMC3616428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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