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Current Perspectives of Telomerase Structure and Function in Eukaryotes with Emerging Views on Telomerase in Human Parasites

24 Jan 2018

Abstract excerpt

Replicative capacity of a cell is strongly correlated with telomere length regulation. Aberrant lengthening or reduction in the length of telomeres can lead to health anomalies, such as cancer or premature aging. Telomerase is a master regulator for maintaining replicative potential in most eukaryotic cells. It does so by controlling telomere length at chromosome ends. Akin to cancer cells, most single-cell...

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Share to Genetics, Aging, and Longevity in Model Organisms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29364142
DOI: 10.3390/ijms19020333

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