Article
The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study.
Atherosclerosis - 1 May 2013
Feitosa Mary F, Wojczynski Mary K, North Kari E, Zhang Qunyuan, Province Michael A, Carr Jeffrey J, Borecki Ingrid B
Abstract excerpt
OBJECTIVES: Nonalcoholic fatty liver disease (NAFLD) ranges from simple steatosis to hepatic inflammation to cirrhosis. We sought to identify common genetic variants contributing to NAFLD, using CT measured fatty liver (FL), and alanine aminotransferase levels (ALT), as a biochemical marker of hepatic inflammation. METHODS: We employed a correlated meta-analysis (CMA) to test whether combining FL and ALT...
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