Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CoupTFI interacts with retinoic acid signaling during cortical development.

PloS one - 1 Jan 2013

Harrison-Uy Susan J, Siegenthaler Julie A, Faedo Andrea, Rubenstein John L R, Pleasure Samuel J

Abstract excerpt

We examined the role of the orphan nuclear hormone receptor CoupTFI in mediating cortical development downstream of meningeal retinoic acid signaling. CoupTFI is a regulator of cortical development known to collaborate with retinoic acid (RA) signaling in other systems. To examine the interaction of CoupTFI and cortical RA signaling we utilized Foxc1-mutant mice in which defects in meningeal development lead to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebral Cortex
Share to Forkhead Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Neurogenesis

Share to Neurons

Share to Stem Cells

Share to Time Factors

Share to Tretinoin

Source

Open in PubMed Open full text

Identifiers

PMID: 23472160
DOI: 10.1371/journal.pone.0058219
PMCID: PMC3589372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CoupTFI interacts with retinoic acid signaling during cortical development.PMID 23472160Read ↗

Evidence that Dmrta2 acts as a transcriptional repressor of <i>Pax6</i> in murine cortical progenitors and identification of a mutation crucial for DNA recognition associated with microcephaly in humanSemantic proximity Read ↗

Cerebrovascular defects in Foxc1 mutants correlate with aberrant WNT and VEGF-A pathways downstream of retinoic acid from the meninges.Semantic proximity Read ↗

Primary cellular meningeal defects cause neocortical dysplasia and dyslamination.Semantic proximity Read ↗

The transcription factor, Pax6, is required for cell proliferation and differentiation in the developing cerebral cortex.Semantic proximity Read ↗

Embryonic signaling centers expressing BMP, WNT and FGF proteins interact to pattern the cerebral cortex.Semantic proximity Read ↗

Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain.Semantic proximity Read ↗

The nuclear orphan receptor COUP-TFI is required for differentiation of subplate neurons and guidance of thalamocortical axons.Semantic proximity Read ↗

Pax6 controls radial glia differentiation in the cerebral cortex.Semantic proximity Read ↗

Dynamic expression of COUP-TFI and COUP-TFII during development and functional maturation of the mouse inner ear.Semantic proximity Read ↗

Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization.Semantic proximity Read ↗

Dorsal telencephalon‐specific <i>RA‐GEF‐1</i> knockout mice develop heterotopic cortical mass and commissural fiber defectSemantic proximity Read ↗

The transcription factor Nfix is essential for normal brain development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.