Article
Concordant and discordant regulation of target genes by miR-31 and its isoforms.
PloS one - 1 Jan 2013
Chan Yu-Tzu, Lin You-Chin, Lin Ruey-Jen, Kuo Huan-Hsien, Thang Wai-Cheng, Chiu Kuo-Ping, Yu Alice L
Abstract excerpt
It has been shown that imprecise cleavage of a primary or precursor RNA by Drosha or Dicer, respectively, may yield a group of microRNA (miRNA) variants designated as "isomiR". Variations in the relative abundance of isoforms for a given miRNA among different species and different cell types beg...
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