Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genetic effect of IL-5 receptor α polymorphism in patients with aspirin-exacerbated respiratory disease.

Experimental & molecular medicine - 8 Mar 2013

Losol Purevsuren, Kim Seung-Hyun, Shin Yoo Seob, Ye Young Min, Park Hae-Sim

Abstract excerpt

Persistent eosinophil activation in both the upper and lower airway mucosa is a central feature of aspirin-exacerbated respiratory disease (AERD). Eosinophil activation and survival are profoundly influenced by interleukin 5 (IL-5) and its receptor, IL-5R. In patients susceptible to allergic disorders, IL-5 receptor α (IL5RA) polymorphisms have been reported; however, an association with AERD remains unclear. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspirin
Share to Electrophoretic Mobility Shift Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Share to Respiration Disorders

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 23470716
DOI: 10.1038/emm.2013.24
PMCID: PMC3641394

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genetic effect of IL-5 receptor α polymorphism in patients with aspirin-exacerbated respiratory disease.PMID 23470716Read ↗

Effect of genetic polymorphism of ALOX15 on aspirin-exacerbated respiratory disease.Semantic proximity Read ↗

Update on recent advances in the management of aspirin exacerbated respiratory disease.Semantic proximity Read ↗

Physiopathology and genetics in aspirin-exacerbated respiratory disease.Semantic proximity Read ↗

A polymorphism of MS4A2 (- 109T > C) encoding the beta-chain of the high-affinity immunoglobulin E receptor (FcepsilonR1beta) is associated with a susceptibility to aspirin-intolerant asthma.Semantic proximity Read ↗

Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma.Semantic proximity Read ↗

Aspirin or other nonsteroidal inflammatory agent exacerbated asthma.Semantic proximity Read ↗

CD55 polymorphisms and risk of aspirin‑exacerbated respiratory disease.Semantic proximity Read ↗

Association of the CCR3 gene polymorphism with aspirin exacerbated respiratory disease.Semantic proximity Read ↗

Leukotriene-related gene polymorphisms in patients with aspirin-intolerant urticaria and aspirin-intolerant asthma: differing contributions of ALOX5 polymorphism in Korean population.Semantic proximity Read ↗

Significant association of FcepsilonRIalpha promoter polymorphisms with aspirin-intolerant chronic urticaria.Semantic proximity Read ↗

Association of ATP8B3 gene polymorphisms with aspirin-exacerbated respiratory disease in asthmatics.Semantic proximity Read ↗

Association of single nucleotide polymorphisms on Interleukin 17 receptor A (IL17RA) gene with aspirin hypersensitivity in asthmatics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.