Article
Association of single nucleotide polymorphisms on Interleukin 17 receptor A (IL17RA) gene with aspirin hypersensitivity in asthmatics.
Human immunology - 1 May 2013
Park Jong Sook, Park Byung Lae, Kim Myung-Ok, Heo Jeong-Seok, Jung Ji-Sun, Bae Da-Jeong, Uh Soo-Taek, Kim Mi-Kyeong, Choi Inseon S, Cho Sang Heon, Hong Chein-Soo, Lee Jae-Young, Choi Byoung Whui, Shin Hyoung Doo, Park Choon-Sik
Abstract excerpt
AIM: To investigate the association of single nucleotide polymorphisms (SNP) on IL17RA gene with Aspirin Exacerbated Respiratory Disease (AERD) and the functional effect of these variants on expression of IL17RA gene products. MATERIAL & METHODS: 15 SNPs of IL17RA gene were analyzed in 825 normal controls and 143 subjects with AERD and 411 with aspirin-tolerant asthma (ATA) and functionally characterized using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
