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Article

Serrated pathway adenocarcinomas: molecular and immunohistochemical insights into their recognition.

PloS one - 1 Jan 2013

Gurzu Simona, Szentirmay Zoltan, Toth Erika, Bara Tivadar, Bara Tivadar, Jung Ioan

Abstract excerpt

INTRODUCTION: Colorectal adenocarcinomas (CRC) developed through serrated pathway seem to present particular behavior compared with the non-serrated ones, but recognition of them is difficult to do. The aim of our paper was to establish some criteria to facilitate their identification. MATERIALS AND METHODS: In 170 consecutive CRCs, we performed immunohistochemical staining with Cytokeratin 7 (CK7) and...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

Share to MutL Protein Homolog 1

Share to Proto-Oncogene Proteins B-raf

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Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 23469219
DOI: 10.1371/journal.pone.0057699
PMCID: PMC3587644

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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