Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Delineating the cytogenomic and epigenomic landscapes of glioma stem cell lines.

PloS one - 1 Jan 2013

Baronchelli Simona, Bentivegna Angela, Redaelli Serena, Riva Gabriele, Butta Valentina, Paoletta Laura, Isimbaldi Giuseppe, Miozzo Monica, Tabano Silvia, Daga Antonio, Marubbi Daniela, Cattaneo Monica, Biunno Ida, Dalprà Leda

Abstract excerpt

Glioblastoma multiforme (GBM), the most common and malignant type of glioma, is characterized by a poor prognosis and the lack of an effective treatment, which are due to a small sub-population of cells with stem-like properties, termed glioma stem cells (GSCs). The term "multiforme" describes the histological features of this tumor, that is, the cellular and morphological heterogeneity. At the molecular level...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Comparative Genomic Hybridization

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique

Share to Glioma

Share to Hydrogen-Ion Concentration

Share to In Situ Hybridization, Fluorescence

Share to Loss of Heterozygosity

Share to Neoplastic Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 23468990
DOI: 10.1371/journal.pone.0057462
PMCID: PMC3585345

Genes

GSC
CAMTA1
EGFR
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Delineating the cytogenomic and epigenomic landscapes of glioma stem cell lines.PMID 23468990Read ↗

Distinctive epigenomes characterize glioma stem cells and their response to differentiation cuesSemantic proximity Read ↗

The Genetic Landscape of Human Glioblastoma and Matched Primary Cancer Stem Cells Reveals Intratumour Similarity and Intertumour HeterogeneitySemantic proximity Read ↗

Emerging Role of Glioma Stem Cells in Mechanisms of Therapy ResistanceSemantic proximity Read ↗

Cancer stem cells in gliomas: evolving concepts and therapeutic implicationsSemantic proximity Read ↗

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.Semantic proximity Read ↗

Different states of stemness of glioblastoma stem cells sustain glioblastoma subtypes indicating novel clinical biomarkers and high-efficacy customized therapiesSemantic proximity Read ↗

Molecular Pathways and Genomic Landscape of Glioblastoma Stem Cells: Opportunities for Targeted TherapySemantic proximity Read ↗

Characterizing the Genomic Profile in High-Grade Gliomas: From Tumor Core to Peritumoral Brain Zone, Passing through Glioma-Derived TumorspheresSemantic proximity Read ↗

Genome-wide profiling of patient-derived glioblastoma stem-like cells reveals recurrent genetic and transcriptomic signatures associated with brain tumorsSemantic proximity Read ↗

Understanding glioma stem cells: rationale, clinical relevance and therapeutic strategiesSemantic proximity Read ↗

Stem cell morphology defines functional heterogeneity and therapeutic vulnerabilities in glioblastomaSemantic proximity Read ↗

Unveiling novel cell clusters and biomarkers in glioblastoma and its peritumoral microenvironment at the single-cell perspectiveSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.