Article
Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function.
PloS one - 1 Jan 2013
Friedrichsen Martin, Poulsen Pernille, Wojtaszewski Jørgen, Hansen Peter Riis, Vaag Allan, Rasmussen Henrik Berg
Abstract excerpt
CONTEXT AND AIMS: Carboxylesterase 1 (CES1) appears to play an important role in the control of the metabolism of triglycerides and cholesterol in adipocytes and other cell types including hepatocytes. Therefore, it is relevant to gain insights into the genetic versus non-genetic mechanisms involved in the control of CES1 mRNA expression. Here, we investigated CES1 mRNA expression level in adipose tissue and its...
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