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Article

High incidence of treatment-induced and vaccine-escape hepatitis B virus mutants among human immunodeficiency virus/hepatitis B-infected patients.

Hepatology (Baltimore, Md.) - 1 Sept 2013

Lacombe Karine, Boyd Anders, Lavocat Fabien, Pichoud Christian, Gozlan Joel, Miailhes Patrick, Lascoux-Combe Caroline, Vernet Guy, Girard Pierre-Marie, Zoulim Fabien

Abstract excerpt

UNLABELLED: Anti-hepatitis B virus (HBV) nucleos(t)ides analogs (NA) exert selective pressures on polymerase (pol) and surface (S) genes, inducing treatment resistance and increasing the risk of vaccine escape mutants. The rate of emergence for these mutations is largely unknown in patients coinf...

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Source

Identifiers

PMID: 23468093
DOI: 10.1002/hep.26374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23468093-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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