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Article

YB-1 interplays with ERα to regulate the stemness and differentiation of ER-positive breast cancer stem cells

1 Jan 2020

Abstract excerpt

Background: Some stemness-associated transcription factors consistently play essential roles in the maintenance of pluripotency or induce the differentiation of cancer stem cells (CSCs). However, the regulatory mechanism of CSC stemness mediated by transcription factors has not been extensively explored. Here, we show that two transcription factors (YB-1 and ER), which are simultaneously highly expressed in...

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PMID: 32206124
DOI: 10.7150/thno.41014

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