Article
Mutant TNFalpha negatively regulates human breast cancer stem cells from MCF7 in vitro.
Cancer biology & therapy - 1 Sept 2007
Li Yaochen, Kong Linghong, Yang Ye, Li Kangsheng
Abstract excerpt
Understanding the biology of breast cancer stem cells and trying new ways to obliterate these cells would be a key step in developing cures for breast cancer. The objective of this study was to investigate the effect of mutant TNFalpha on human breast cancer stem cells derived from MCF7 cell line under the characterization of biologic features of these cells in vitro. By FACS analysis and sorting, we got MCF7...
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