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Article

Spontaneous osteoarthritis in Str/ort mice is unlikely due to greater vulnerability to mechanical trauma.

Osteoarthritis and cartilage - 1 May 2013

Poulet B, Westerhof T A T, Hamilton R W, Shefelbine S J, Pitsillides A A

Abstract excerpt

OBJECTIVE: Relative contributions of genetic and mechanical factors to osteoarthritis (OA) remain ill-defined. We have used a joint loading model found to produce focal articular cartilage (AC) lesions, to address whether genetic susceptibility to OA in Str/ort mice is related to AC vulnerability to mechanical trauma and whether joint loading influences spontaneous OA development. We also develop finite element...

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Source

Identifiers

PMID: 23467034
DOI: 10.1016/j.joca.2013.02.652

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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