Article
Cartilage damage pattern in relation to subchondral plate thickness in a collagenase-induced model of osteoarthritis.
Osteoarthritis and cartilage - 1 Apr 2008
Botter S M, van Osch G J V M, Waarsing J H, van der Linden J C, Verhaar J A N, Pols H A P, van Leeuwen J P T M, Weinans H
Abstract excerpt
OBJECTIVE: To see how initial differences in subchondral bone phenotype influence the development of cartilage damage and changes in subchondral bone architecture in an osteoarthritis (OA)-induced mouse model. METHOD: Intra-articular collagenase injections (right knee joint) and saline controls (left knee joint) were applied in the knees of two mouse strains known to have either a low or a high bone mass...
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