Article
Gene variants in angiogenesis and lymphangiogenesis and cutaneous melanoma progression.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2013
Park Jong Y, Amankwah Ernest K, Anic Gabriella M, Lin Hui-Yi, Walls Brooke, Park Hyun, Krebs Kevin, Madden Melissa, Maddox Kristen, Marzban Suroosh, Fang Shenying, Chen Wei, Lee Jeffrey E, Wei Qingyi, Amos Christopher I, Messina Jane L, Sondak Vernon K, Sellers Thomas A, Egan Kathleen M
Abstract excerpt
BACKGROUND: Angiogenesis and lymphangiogenesis are important in the progression of melanoma. We investigated associations between genetic variants in these pathways with sentinel lymph node (SLN) metastasis and mortality in 2 independent series of patients with melanoma. METHODS: Participants at Moffitt Cancer Center were 552 patients, all Caucasian, with primary cutaneous melanoma referred for SLN biopsy. A...
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