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Article

Next generation sequencing reveals the association of DRB3*02:02 with type 1 diabetes.

Diabetes - 1 Jul 2013

Erlich Henry A, Valdes Ana Maria, McDevitt Shana L, Simen Birgitte B, Blake Lisbeth A, McGowan Kim R, Todd John A, Rich Stephen S, Noble Janelle A

Abstract excerpt

The primary associations of the HLA class II genes, HLA-DRB1 and HLA-DQB1, and the class I genes, HLA-A and HLA-B, with type 1 diabetes (T1D) are well established. However, the role of polymorphism at the HLA-DRB3, HLA-DRB4, and HLA-DRB5 loci remains unclear. In two separate studies, one of 500 subjects and 500 control subjects and one of 366 DRB1*03:01-positive samples from selected multiplex T1D families, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23462545
DOI: 10.2337/db12-1387
PMCID: PMC3712046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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