Article

Contrasting macroevolutionary patterns in the human N-glycosylation pathway

2024-10-31

Abstract excerpt

Building on coding mutations and splicing variants, post-translational modifications add a final layer to protein diversity that operates at developmental and physiological timescales. Although protein glycosylation is one of the most common post-translational modifications, its evolutionary origin remains largely unexplored. Here, we performed a phylostratigraphic tracking of glycosylation machinery genes and the...

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Literature Corpus work: 680f45a3-2030-5ea0-9ead-46ef19df52b7
DOI: 10.1101/2024.10.30.621208

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