Article
Emerging methods in protein co-evolution.
Nature reviews. Genetics - 1 Apr 2013
de Juan David, Pazos Florencio, Valencia Alfonso
Abstract excerpt
Co-evolution is a fundamental component of the theory of evolution and is essential for understanding the relationships between species in complex ecological networks. A wide range of co-evolution-inspired computational methods has been designed to predict molecular interactions, but it is only recently that important advances have been made. Breakthroughs in the handling of phylogenetic information and in...
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