Article
Association of an MHC class II haplotype with increased risk of polymyositis in Hungarian Vizsla dogs.
PloS one - 1 Jan 2013
Massey Jonathan, Rothwell Simon, Rusbridge Clare, Tauro Anna, Addicott Diane, Chinoy Hector, Cooper Robert G, Ollier William E R, Kennedy Lorna J
Abstract excerpt
A breed-specific polymyositis is frequently observed in the Hungarian Vizsla. Beneficial clinical response to immunosuppressive therapies has been demonstrated which points to an immune-mediated aetiology. Canine inflammatory myopathies share clinical and histological similarities with the human immune-mediated myopathies. As MHC class II associations have been reported in the human conditions we investigated...
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