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Article

The role of mitochondria in aging.

The Journal of clinical investigation - 1 Mar 2013

Bratic Ana, Larsson Nils-Göran

Abstract excerpt

Over the last decade, accumulating evidence has suggested a causative link between mitochondrial dysfunction and major phenotypes associated with aging. Somatic mitochondrial DNA (mtDNA) mutations and respiratory chain dysfunction accompany normal aging, but the first direct experimental evidence...

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Identifiers

PMID: 23454757
DOI: 10.1172/JCI64125
PMCID: PMC3582127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23454757-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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