Article
Mosaic analysis with double markers reveals cell-type-specific paternal growth dominance.
Cell reports - 28 Mar 2013
Hippenmeyer Simon, Johnson Randy L, Luo Liqun
Abstract excerpt
Genomic imprinting leads to preferred expression of either the maternal or paternal alleles of a subset of genes. Imprinting is essential for mammalian development, and its deregulation causes many diseases. However, the functional relevance of imprinting at the cellular level is poorly understood for most imprinted genes. We used mosaic analysis with double markers (MADM) in mice to create uniparental disomies...
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