Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TNRC9 downregulates BRCA1 expression and promotes breast cancer aggressiveness.

Cancer research - 1 May 2013

Shan Jingxuan, Dsouza Shoba P, Bakhru Sasha, Al-Azwani Eman K, Ascierto Maria L, Sastry Konduru S, Bedri Shahinaz, Kizhakayil Dhanya, Aigha Idil I, Malek Joel, Al-Bozom Issam, Gehani Salah, Furtado Stacia, Mathiowitz Edith, Wang Ena, Marincola Francesco M, Chouchane Lotfi

Abstract excerpt

Although the linkage between germline mutations of BRCA1 and hereditary breast/ovarian cancers is well established, recent evidence suggests that altered expression of wild-type BRCA1 might contribute to the sporadic forms of breast cancer. The breast cancer gene trinucleotide-repeat-containing 9...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis Regulatory Proteins
Share to Cyclic AMP Response Element-Binding Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Genes, BRCA1

Share to High Mobility Group Proteins

Share to Neoplasm Invasiveness

Share to Neoplasm Metastasis

Share to Receptors, Progesterone

Source

Identifiers

PMID: 23447579
DOI: 10.1158/0008-5472.CAN-12-4313

Genes

BRCA1
TOX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23447579-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TNRC9 downregulates BRCA1 expression and promotes breast cancer aggressiveness.PMID 23447579Read ↗

Harnessing AI to Reveal CTNNB1’s Central Role in Breast Cancer Progression and Drug DiscoverySemantic proximity Read ↗

Genetic variants in trinucleotide repeat-containing 9 (TNRC9) are associated with risk of estrogen receptor positive breast cancer in a Chinese population.Semantic proximity Read ↗

Integrative analysis of genomic alterations in triple-negative breast cancer in association with homologous recombination deficiency.Semantic proximity Read ↗

Exploring ID4 as a Driver of Aggression and a Therapeutic Target in Triple-Negative Breast CancerSemantic proximity Read ↗

Oncogenic HJURP is driven by P53/ E2F1/FOXM1-axis regulated enhancer and potentiates TNBC proliferation and invasionSemantic proximity Read ↗

Association between polymorphisms of trinucleotide repeat containing 9 gene and breast cancer risk: evidence from 62,005 subjects.Semantic proximity Read ↗

WNT10B/β‐catenin signalling induces HMGA2 and proliferation in metastatic triple‐negative breast cancerSemantic proximity Read ↗

Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumorsSemantic proximity Read ↗

Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumorsSemantic proximity Read ↗

The WNT10B Network Is Associated with Survival and Metastases in Chemoresistant Triple-Negative Breast Cancer.Semantic proximity Read ↗

Adjuvant Capecitabine-Containing Chemotherapy Benefit and Homologous Recombination Deficiency Status Among Early-Stage TNBC Patients in the FinXX trialSemantic proximity Read ↗

Homer3 Promotes Aggressive Phenotypes in Triple-Negative Breast Cancer Through Cell Cycle- and MYC-Associated Programs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.